Endocrine Abstracts

Background: We describe a 64-year-old lady with past medical history of Thalassaemia Trait and Hypertension, who was presented with Cushing’s syndrome.Clinical presentation: This patient was admitted with severe bi-basal pneumonia in February 2010 and treated successfully. But unfortunately her symptoms persisted with increasing facial swelling in end of May 2010, therefore, a staging CT was arranged and found incidental 6×5 cm left adrenal mas...

A 51-year-old asymptomatic man presented in 1998 with elevated thyroid stimulating hormone (TSH) 6.34 mIU/l (0.34–5.6 mIU/l), FT4 54.1 pmol/l (7.5–21.1 pmol/l), FT3 20.1 pmol/l (3.0–5.0 pmol/l) and TSH-α subunits 3.6 mcg/l (<2.0 mcg/l). After the first visit, he was lost to follow-up.He presented 10 years later in 2008 with 1-week history of symptoms of heart failure and hyperthyroidism. Clinically he was thy...

Ectopic ACTH secretion accounts for 11–25% of Cushing’s syndrome, most commonly resulting from small cell lung carcinoma and bronchial carcinoid tumours. Ectopic ACTH requires meticulous consideration in the differential of ACTH-dependent Cushing’s syndrome. Thymic carcinoids are a very rare cause of ectopic ACTH secretion, accounting for 5–12% of cases. A 28 year old gentleman was diagnosed with Cushing’s syndrome after presenting with lethargy, hyper...